Modern malware and spyware platforms attack existing antivirus solutions and even Microsoft PatchGuard. To protect users and business systems new technologies developed by Intel and AMD CPUs may be applied. To deal with the new malware we propose monitoring and controlling access to the memory in real time using Intel VT-x with EPT. We have checked this concept by developing MemoryMonRWX, which is a bare-metal hypervisor. MemoryMonRWX is able to track and trap all types of memory access: read, write, and execute. MemoryMonRWX also has the following competitive advantages: fine-grained analysis, support of multi-core CPUs and 64-bit Windows 10. MemoryMonRWX is able to protect critical kernel memory areas even when PatchGuard has been disabled by malware. Its main innovative features are as follows: guaranteed interception of every memory access, resilience, and low performance degradation.